Oroxin A
CAS No. : 57396-78-8
| Size | Price | Stock |
|---|---|---|
| 1mg | $47 | In-stock |
| 5mg | $99 | In-stock |
| 10mg | $168 | In-stock |
| 25mg | $283 | In-stock |
| 50mg | $445 | In-stock |
| 100mg | $645 | In-stock |
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| Cat. No. : | HY-N2025 |
| M.Wt: | 432.38 |
| Formula: | C21H20O10 |
| Purity: | >98 % |
| Solubility: | DMSO : 125 mg/mL (ultrasonic) |
Oroxin A is the major component of an ethanol-water Oroxylum indicum (L.) Kurz (Bignoniaceae) seed extract (OISE). Oroxin A acts as a partial PPARγ agonist that can activate PPARγ transcriptional activation. Oroxin A activates PPARγ by docking into the PPARγ protein ligand-binding domain. Oroxin A also exhibits an inhibitory activity against α-glucosidase and an antioxidant capacity[1]. Oroxin A exerts anti-breast cancer effects by inducing ER stress-mediated senescence[2]. In Vitro: Oroxin A (0.5- 100 μM; 24 hours) significantly increases the PPARγ transcription level and exhibits the strongest activation with 50 μM in HEK-293t cells[1].
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