Naftopidil
CAS No. : 57149-07-2
(Synonyms: KT-611; BM-15275)
| Size | Price | Stock |
|---|---|---|
| 500mg | $50 | In-stock |
| 1g | $80 | In-stock |
| 5g | $108 | In-stock |
| 10g | $180 | In-stock |
| 50 g | Get quote | |
| 100 g | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
or Fax: (86)21-58955996
Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-B0391 |
| M.Wt: | 392.49 |
| Formula: | C24H28N2O3 |
| Purity: | >98 % |
| Solubility: | H2O : < 0.1 mg/mL;DMSO : 33.33 mg/mL (ultrasonic) |
Naftopidil (KT-611) is is a selective alpha1-adrenoceptor antagonist, with Kis of 3.7 nM, 20 nM and 1.2 nM for the cloned human α1a-, α1b- and α1d-adrenoceptor subtypes, respectively. Naftopidil has antiproliferative effects. Naftopidil can be used for the research of prostate hyperplasia[1][2].
IC50 & Target:α1-adrenoceptor[1]
In Vitro: Naftopidil suppresses human prostate tumor growth by altering interactions between tumor cells and stroma[2].
Naftopidil (10 μM for PCa cells, 0.1-10 μM for PrSC; 3 days) shows growth inhibitory effects on PCa cells and PrSC[2].
Naftopidil (50 μM for E9 cells, 25 μM for PrSC; 48 hours) increases the level of cell-cycle regulatory protein p27 in E9 cells, but not PrSC[2].
In Vivo: Naftopidil (10 mg/kg; p.o; daily; for 28 days) decreases microvessel density (MVD) in E9+PrSC tumors mice model[2].
Lorem ipsum dolor sit amet, consectetur adipisicing elit. Autem earum hic iste maiores, nam neque rem suscipit. Adipisci consequatur error exercitationem fugit ipsam optio qui, quibusdam repellendus sed vero! Debitis.
Inquiry Information- Product Name:
- Naftopidil
- Cat. No.:
- HY-B0391
- Quantity:
Your information is safe with us.