Isonixin
CAS No. : 57021-61-1
(Synonyms: Isonixine; Nixyn)
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| Cat. No. : | HY-105579 |
| M.Wt: | 242.27 |
| Formula: | C14H14N2O2 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Isonixin (Isonixine) is a non-steroidal compound. Isonixin can be used for the research of pain and inflammation[1][2][3][4]. In Vivo: Isonixine potentiates hexobarbital sleep time, reduces motor activity, antagonizes cardiazol-induced convulsions, causes hyperthermia, and inhibits tremorine-induced trembling in mice[1]. Isonixine (p.o.) showes a 3.15 h half-life of absorption and rapidly absorbs in a gastro-intestinal tract[2]. Isonixine (i.v., intragastrically and intraduodenally) mainly excrets via urine, and isonixine can be eliminated by urine within 50 hours[3]. Isonixine (2000 mg/kg; p.o. once daily for 6 months) presents some mild toxic effects and induces no gastrointestinal lesion in male rabbits and rats[4].
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