Sulfinpyrazone


CAS No. : 57-96-5

(Synonyms: G-28315)

57-96-5
Price and Availability of CAS No. : 57-96-5
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Cat. No. : HY-B1271
M.Wt: 404.48
Formula: C23H20N2O3S
Purity: >98 %
Solubility: DMSO : 33.33 mg/mL (ultrasonic)
Introduction of 57-96-5 :

Sulfinpyrazone (G-28315) is an orally active and potent uricosuric agent for chronic and intermittent gouty arthritis. Sulfinpyrazone has antithrombotic and platelet inhibitory effects[1][2]. In Vitro: Sulfinpyrazone (G-28315) stimulates fibrinolytic activity[2]. In Vivo: In rats with kaolin-induced paw oedema, Sulfinpyrazone (G-28315) is able to restore the markedly prolonged euglobulin clot lysis time in an oral dose of 30 mg/kg. Beside these effects, Sulfinpyrazone protects rabbits from arachidonate-induced sudden death after a single oral dose of 10-30 mg/kg[2].

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