Sulfamethazine
CAS No. : 57-68-1
(Synonyms: Sulfadimidine; Sulfadimerazine)
| Size | Price | Stock |
|---|---|---|
| 500mg | $55 | In-stock |
| 1g | $60 | In-stock |
| 5g | $100 | In-stock |
| 10g | $130 | In-stock |
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| 100 g | Get quote | |
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| Cat. No. : | HY-B0035 |
| M.Wt: | 278.33 |
| Formula: | C12H14N4O2S |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
Sulfamethazine (Sulfadimidine) is a brain-penetrant sulfonamide antibiotic. Sulfamethazine inhibits bacterial growth by blocking the synthesis of folic acid. Sulfamethazine can be used for research on bacterial infections[1][2].
IC50 & Target:Bacterial[1]
In Vivo:Sulfamethazine (0.3 g/kg; i.m.; single dose) demonstrates restricted passage across the blood-brain barrier in adult pregnant and non-pregnant Wistar rats, with brain levels consistently reaching 30-37% of corresponding blood levels[1].
Sulfamethazine (80 mg/kg; i.v.; single dose) treatment significantly reduced α, β and AUC0-∞, and significantly increased t1/2α, Vd and CIB, with an absolute bioavailability of 1.01[2].
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