Ethinylestradiol
CAS No. : 57-63-6
(Synonyms: Ethynyl estradiol; 17α-Ethynylestradiol)
| Size | Price | Stock |
|---|---|---|
| 500mg | $30 | In-stock |
| 1g | $58 | In-stock |
| 5g | $184 | In-stock |
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| Cat. No. : | HY-B0216 |
| M.Wt: | 296.40 |
| Formula: | C20H24O2 |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 100 mg/mL;H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 80°C) |
Ethinylestradiol is an orally active steroidal estrogen. Ethinylestradiol is widely used in research on menopausal symptoms, gynecological conditions, and certain hormone-sensitive cancers[1].
In Vitro:Ethinylestradiol (0.01-10 nM, 24-48 h) increases cGMP formation in RFL6 cells[2].
Ethinylestradiol (0.01-10 nM, 6-48 h) reduces superoxide anion production in BAEC cells in dose- and time-dependent manner[2].
Ethinylestradiol (1-100 nM, 24 h) decreases mRNA (XPC and XPA) abundance and NER capacity in zebrfish liver cells[3].
In Vivo:Ethinylestradiol (5 mg/kg, s.c., 5 days) increases synthesis and expression of low density lipoprotein-receptor
in the liver of female Sprague-Dawley rats at pharmacological doses[4].
Ethinylestradiol (0-50 μg/kg, i.g., daily, 21 days) can have adverse effects on the reproductive development of nulliparous female Wistar rats[5].
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