Benactyzine hydrochloride


CAS No. : 57-37-4

57-37-4
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Cat. No. : HY-B1542A
M.Wt: 363.88
Formula: C20H26ClNO3
Purity: >98 %
Solubility: DMSO : 150 mg/mL (ultrasonic;warming);H2O : 50 mg/mL (ultrasonic)
Introduction of 57-37-4 :

Benactyzine hydrochloride is a competitive BChE inhibitor with a Ki of 0.01 mM. Benactyzine hydrochloride is an anticholinergic drug. Benactyzine hydrochloride has the potential for organophosphate poisoning research[1][2]. In Vivo:Benactyzine hydrochloride (1 mg/kg) does not influence the attention response. Benactyzine hydrochloride increases the duration of the exploratory-motor reaction, but slightly diminishes the salivation elicited by acetylcholine. There is no blocking effect of Benactyzine hydrochloride and promazine on the EEG-seizure activity elicited by acetylcholine, and almost no inhibitory effect on emotional reactions. Emotional reactions are blocked by high doses of imipramine and promazine, but not by Benactyzine hydrochloride[2].

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