Stearic acid
CAS No. : 57-11-4
| Size | Price | Stock |
|---|---|---|
| 500mg | $25 | In-stock |
| 5g | $35 | In-stock |
| 10g | $50 | In-stock |
| 25g | $80 | In-stock |
| 50g | $112 | In-stock |
| 100g | $156 | In-stock |
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| Cat. No. : | HY-B2219 |
| M.Wt: | 284.48 |
| Formula: | C18H36O2 |
| Purity: | >98 % |
| Solubility: | Ethanol : 25 mg/mL (ultrasonic) |
Stearic acid is an orally active long-chain dietary saturated fatty acid that can significantly reduce visceral fat by inducing apoptosis of preadipocytes. Stearic acid can be used in the study of cardiovascular and metabolic diseases[1]. In Vitro:Stearic acid (50 μM; 48 h) increases apoptosis of 3T3L1 preadipocytes, decreases the expression of cIAP2 and Bcl2, and increases the expression of Bax[1]. Stearic acid (0-200 μM; 48 h) shows a dose-dependent cytotoxicity to 3T3L1 preadipocytes starting at 35 μM and reaching a maximum at 100 μM, and increases caspase-3 activity in preadipocytes after 48 h of treatment[1]. In Vivo:Stearic acid (17% stearic acid/3% safflower oil diet, p.o.; ad libitum; 18 weeks and 3 days) reduces bone mineral density, abdominal fat content, and serum glucose concentration, and increases serum monocyte chemoattractant protein-1 levels in female athymic mice[1].
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