MGS0039
CAS No. : 569686-87-9
(Synonyms: BCI 632)
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| Cat. No. : | HY-123411 |
| M.Wt: | 378.18 |
| Formula: | C15H14Cl2FNO5 |
| Purity: | >98 % |
| Solubility: |
MGS0039 is a type II group mGluR antagonist. MGS0039 has a high affinity for mGluR2 and mGluR3, with Ki values of 2.2 nM and 4.5 nM, respectively. MGS0039 can attenuate the inhibitory effect of glutamate-induced cyclic AMP formation triggered by Forskolin (HY-15371) in CHO cells expressing mGluR2/mGluR3. MGS0039 shows antidepressant-like activity in rats[1].
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