Penduletin
CAS No. : 569-80-2
| Size | Price | Stock |
|---|---|---|
| 1mg | $380 | In-stock |
| 5mg | $970 | Get quote |
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| Cat. No. : | HY-N3096 |
| M.Wt: | 344.32 |
| Formula: | C18H16O7 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Penduletin is a flavone, that can be isolated from Brickelia pendula and Vitex negundo. Penduletin shows anticancer activity. Penduletin induces apoptosis in the cancer cells through ROS generation[1][2].
In Vitro: Penduletin (0-100 µg/mL, 48 h) shows antiproliferative activity against HepG2 and MCF-7 cell lines, with IC50 values of 25.8, and 6.4 µM, respectively[1].
Penduletin exhibits an enhanced ability to induce the cleavage of procaspase‐3 in HepG2 and both procaspase‐3 and procaspase‐8 in MCF-7 cells line[1].
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