Eperisone (hydrochloride)
CAS No. : 56839-43-1
(Synonyms: (±)-Eperisone (hydrochloride))
| Size | Price | Stock |
|---|---|---|
| 25mg | $30 | In-stock |
| 50mg | $50 | In-stock |
| 100mg | $80 | In-stock |
| 500mg | $200 | In-stock |
| 1g | $300 | In-stock |
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| Cat. No. : | HY-B1901 |
| M.Wt: | 295.85 |
| Formula: | C17H26ClNO |
| Purity: | >98 % |
| Solubility: | DMSO : 31.25 mg/mL (ultrasonic);H2O : 100 mg/mL (ultrasonic) |
Eperisone Hydrochloride ((±)-Eperisone hydrochloride) is an orally active antispastic agent with a vasodilator effect, used for the research of muscle stiffness and pain. Eperisone Hydrochloride is a potent and selectively P2X7 receptor antagonist, also shows antagonism for human P2X3. Eperisone Hydrochloride works by relaxing both skeletal muscles and vascularsmooth muscles, demonstrating a variety of effects such as reduction ofmyotonia, improvement of circulationand and suppression of the pain reflex[1][2][3][4][5][6].
In Vitro:Eperisone Hydrochloride (0--200 µM, 18-72 h) preferentially suppresses lung fibroblast activity, but is not toxic to alveolar epithelial cells in vitro[5].
In Vivo:Eperisone Hydrochloride (15 or 50 mg/kg, p.o., a single dose for 9 days) suppresses Bleomycin (BLM) (HY-108345)-dependent pulmonary fibrosis through its inhibitory effect on fibroblast activation in the lungs of mice[5].
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