Cefmetazole
CAS No. : 56796-20-4
(Synonyms: CS 1170)
| Size | Price | Stock |
|---|---|---|
| 5mg | $76 | In-stock |
| 10mg | $121 | In-stock |
| 25mg | $242 | In-stock |
| 50mg | $388 | In-stock |
| 100mg | $620 | In-stock |
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| Cat. No. : | HY-B1595 |
| M.Wt: | 471.53 |
| Formula: | C15H17N7O5S3 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Cefmetazole (CS 1170) is a semisynthetic cephamycin antibiotic with broad-spectrum antibacterial activity, covering gram-positive, gram-negative and anaerobic bacteria. Cefmetazole binds to penicillin binding proteins (PBPs), resulting in interfering bacterial cell wall biosynthesis. Cefmetazole is used for the research of gynecologic, intraabdominal, urinary tract, respiratory tract and skin and soft tissue infections[1][2][3]. In Vitro: Cefmetazole (CS 1170) has antibiotic affinity to S. aureus with a MIC value of 1.0 mg/L. Cefmetazole has affinity for PBP1, PBP2 and PBP3 with IC50 values of ≤0.3, 0.109 and 0.494 mg/L[1]. In Vivo: Cefmetazole (CS 1170) (100 mg/kg; i.h.; twice a day, for 7 days; male ICR mice) alters gut bacterial flora[3].
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