PluriSIn #2
CAS No. : 56563-17-8
| Size | Price | Stock |
|---|---|---|
| 5mg | $250 | In-stock |
| 10mg | $450 | In-stock |
| 25mg | $850 | In-stock |
| 50mg | $1350 | In-stock |
| 100mg | $1950 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-111630 |
| M.Wt: | 249.20 |
| Formula: | C11H8FN3O3 |
| Purity: | >98 % |
| Solubility: | DMSO : 5 mg/mL (ultrasonic) |
PluriSIn #2 is a selective transcriptional inhibitor of topoisomerase II α (TOP2A). PluriSIn #2 is a compound that selectively eliminates undifferentiated human pluripotent stem cells (hPSCs)[1].
In Vitro: PluriSIn #2 (20 µM; 12 hours) treatment reduces TOP2A expression at the protein level[1].
A 24h exposure of PluriSIn #2 (20 µM) is sufficient to induce massive cell death in hPSCs, but doesn’t affect the viability of various other cell types derived from them[1].
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