Dimethindene
CAS No. : 5636-83-9
| Size | Price | Stock |
|---|---|---|
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| 10mg | $140 | In-stock |
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| Cat. No. : | HY-13710 |
| M.Wt: | 292.42 |
| Formula: | C20H24N2 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Dimethindene is a potent, selective histamine H1 antagonist. Dimethindene impairs cutaneous wound healing (WH). Dimethindene can block K+ currents[1][2]. In Vitro: Dimethindene (5-500 μM; follicle-enclosed Xenopus oocytes) decreases Cromakalim cromakalim-induced K+ currents with an IC50 value of 29.5 μM[2]. In Vivo: Dimethindene (0.25 mg; i.p.; once; C57BL/6 mice with skin WH) impaires cutaneous wound healing (WH) and delays skin wound closure[1].
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