Aloperine
CAS No. : 56293-29-9
| Size | Price | Stock |
|---|---|---|
| 25mg | $34 | In-stock |
| 50mg | $55 | In-stock |
| 100mg | $90 | In-stock |
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| Cat. No. : | HY-13516 |
| M.Wt: | 232.37 |
| Formula: | C15H24N2 |
| Purity: | >98 % |
| Solubility: | DMSO : 5.56 mg/mL (ultrasonic;warming;heat to 60°C) |
Aloperine is an alkaloid in sophora plants such as Sophora alopecuroides L, which has shown anti-cancer, anti-inflammatory and anti-virus properties[1]. Aloperine is widely used to treat patients with allergic contact dermatitis eczema and other skin inflammation in China[2]. Aloperine induces apoptosis and autophagy in HL-60 cells[1]. In Vitro:Aloperine (1-20 μM; 24 hours) gives growth-inhibitory IC50 values in cancer cells ranges from 0.04 to 1.36 mM, the IC50 values in HL-60, U937, K562, EC109, A549 and HepG2 cells are 0.04, 0.27, 0.36, 1.11, 1.18 and 1.36 mM,respectively[1]. Aloperine (1-20 μM; 24 hours) induces apoptosis and decreases bcl-2 expression in HL-60 cells[1]. Aloperine (20–100 μM; 18 hours) induces autophagy and formation of acidic vacuole in HL-60 cells[1].
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