Indacrinone


CAS No. : 56049-88-8

(Synonyms: MK-196; Indacrynic acid)

56049-88-8
Price and Availability of CAS No. : 56049-88-8
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5mg $400 In-stock
10mg $640 In-stock
25mg $1280 In-stock
50mg $2050 In-stock
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Cat. No. : HY-U00242
M.Wt: 365.21
Formula: C18H14Cl2O4
Purity: >98 %
Solubility: DMSO : 125 mg/mL (ultrasonic)
Introduction of 56049-88-8 :

Indacrinone (MK196) is an investigational diuretic which has pronounced saluretic activity in the rat and dog as well as both uricosuric and saluretic activity in the chimpanzee. In Vivo: As the dose increasing from 1 to 10 mg/kg, the amount excreted via the urine decreased from 20 to 11% of administered dose. The amount excretes via the feces is 2-fold higher at the lower dose. At the 10 mg/kg dose the Indacrinone (MK-196)/1 ratio is 0.8 and 5 for the urine and feces, respectively. The urinary ratio of Indacrinone/1 decrease as dose increasing from 10 mg/kg (0.5) to 20 mg/kg (0.2)[1].

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