L-Lysine

L-lysine is an essential amino acid for humans with orally activity. L-lysine can inhibit the occurrence of HSV infections and is used in herpes research. L-lysine increases calcium absorption, reduces diabetes-related diseases, improves gut health, and alleviates pancreatic inflammation. L-lysine can be used in research on metabolism, infection, and inflammation^[1][2][3][4]. IC50 & Target:L-lysine (150 mg/kg) promotes, but not initiates, bladder cancer. The administration of L-lysine to rats submitted to colovesical cystoplasty accelerates the development of transitional metaplasia of the intestinal epithelium^[1].
L-lysine (10 mg/kg) treatment attenuates pancreatic tissue injury induced by L-arginine by inhibiting the release of the inflammatory cytokine IL-6 and enhance antioxidant activity^[2]. In Vivo:L-lysine (5 or 10 mg/kg, p.o., single dose) ameliorates sepsis-induced acute lung injury in a lipopolysaccharide (HY-D1056)-induced mouse model^[3]. L-lysine (10 mg/kg, p.o., once daily for 45 days) treatment attenuates pancreatic tissue injury by inhibiting the release of the inflammatory cytokine IL-6, and enhances antioxidant activity in L-Arginine hydrochloride (HY-N0455A)-induced acute pancreatitis mice model^[4].