L-Glutamic acid
CAS No. : 56-86-0
| Size | Price | Stock |
|---|---|---|
| 250g | $20 | In-stock |
| 500g | $28 | In-stock |
| 1000g | $53 | In-stock |
| > 2 kg | Get quote | |
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| Cat. No. : | HY-14608 |
| M.Wt: | 147.13 |
| Formula: | C5H9NO4 |
| Purity: | >98 % |
| Solubility: | H2O : 6.25 mg/mL (ultrasonic);DMSO : < 1 mg/mL (ultrasonic;warming;heat to 60°C) |
L-Glutamic acid is an excitatory amino acid neurotransmitter that acts as an agonist for all subtypes of glutamate receptors (metabolic rhodophylline, NMDA, and AMPA). L-Glutamic acid has an agonist effect on the release of DA from dopaminergic nerve endings. L-Glutamic acid can be used in the study of neurological diseases. L-Glutamic acid acts at ionotropic and metabotropic glutamate receptors[1][2][3][4][5].
IC50 & Target:DA[1].
In Vitro:L-Glutamic acid (120, 500, 750, 1000 mg/dL) can reduce the harmful effect of lithium on the embryonic development of Xenopus Xenopus[3].
L-Glutamic acid (2, 5, 10, 20 mM, 24-48 h) can induce neuroexcitotoxicity in neuroblastoma[4].
In Vivo:L-Glutamic acid (3 g/kg, subcutaneous injection) can promote excitotoxic degeneration of retinal ganglion cells in mice[1].
L-Glutamic acid (750 mg/kg, intraperitoneal injection) can reduce and inhibit oxidative stress induced by chlorpyrifos (CPF) in rats[5].
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