Biguanide
CAS No. : 56-03-1
| Size | Price | Stock |
|---|---|---|
| 25mg | $58 | In-stock |
| 50mg | $92 | In-stock |
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| Cat. No. : | HY-121006 |
| M.Wt: | 101.11 |
| Formula: | C2H7N5 |
| Purity: | >98 % |
| Solubility: |
Biguanide is an orally active antihyperglycemic agent. Biguanide inhibits mitochondrial ATP production, activates the LKB1-AMPK signaling pathway, and damages the energy homeostasis. Biguanide enhances insulin-receptor activation and downstream signaling. Biguanide exhibits potential in ameliorating the type 2 diabetes and the insulin-associated cancers[1]. In Vitro:Biguanide (100-200 μM, 3 h) increases intracellular/extracellular metformin concentration ratio of about 5-fold in mouse hepatocytes[2].
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