Clebopride
CAS No. : 55905-53-8
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| Cat. No. : | HY-B1613 |
| M.Wt: | 373.88 |
| Formula: | C20H24ClN3O2 |
| Purity: | >98 % |
| Solubility: |
Clebopride is an orally active dopamine Receptor antagonist. Clebopride acts on dopamine D2 receptors and has antiemetic and prokinetic effects. Clebopride can be used in the study of functional gastrointestinal disorders[1][2][3][4].
In Vitro:Clebopride (0.1 nM-10μM, 30 min) selectively binds to D2 dopamine receptors (Ki: 3.5 nM) and α2 adrenergic receptors (Ki: 780 nM) in bovine brain membranes[3].
Clebopride inhibits ETS-induced gastric strip contractions (IC50: 0.43 μM) [3].
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