Crocin II
CAS No. : 55750-84-0
| Size | Price | Stock |
|---|---|---|
| 1mg | $40 | In-stock |
| 5mg | $80 | In-stock |
| 10mg | $120 | In-stock |
| 20mg | $190 | In-stock |
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| Cat. No. : | HY-N0698 |
| M.Wt: | 814.82 |
| Formula: | C38H54O19 |
| Purity: | >98 % |
| Solubility: | DMSO : 25 mg/mL (ultrasonic) |
Crocin II is an inhibitor targeting α-synuclein aggregation, with a IC50 of 0.541 μM and a EC50 of 3.63 μM. Crocin II inhibits α-synuclein aggregation and dissociates pre-formed α-synuclein fibrils. Crocin II possesses antioxidant, anticancer and antidepressant activities. Crocin II is applicable to research related to neurological disorders such as Parkinson's disease, dementia with Lewy bodies and multiple system atrophy, as well as cancers[1][2][3].
IC50 & Target:IC50: 31.3 μM (NO production)[1]
In Vitro:Crocin II (3 h) inhibits α-synuclein aggregation in vitro with an IC50 of 0.541 μM[1].
Crocin II (15 min) disassembles preformed α-synuclein fibrils in vitro, with an EC50 of 3.63 μM[1].
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