Litorin
CAS No. : 55749-97-8
| Size | Price | Stock |
|---|---|---|
| 1mg | $70 | In-stock |
| 5mg | $200 | In-stock |
| 10mg | $300 | In-stock |
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| Cat. No. : | HY-103281 |
| M.Wt: | 1085.24 |
| Formula: | C51H68N14O11S |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic);H2O : 2 mg/mL (ultrasonic;warming;adjust pH to 3 with HCl;heat to 60°C) |
Litorin, an amphibian bombesin peptide derivative, is an bombesin receptor agonist. Litorin stimulates the contraction of smooth muscle, stimulates gastrin, gastric acid, and pancreatic secretion, and suppresses the nutriment in vivo[1][2].
In Vitro: 99mTc-Litorin is developed for non-invasive imaging of tumors with overexpressed gastrin-releasing peptide receptors (GRP-R)[1].
[D-Phe1,Leu8,9]Litorin inhibits binding of 125I-[Tyr4] BN to murine Swiss 3T3 cells with a Ki of 5.1 nM[2].
Litorin stimulates 3H-Thymidine incorporation in murine Swiss 3T3 cells with an EC50 of 2.3 nM[2].
In Vivo: Litorin stimulates the contraction of smooth muscle, stimulates gastrin, gastric acid, and pancreatic secretion, and suppresses the nutriment in in vivo experiments[2].
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