TCN 213


CAS No. : 556803-08-8

556803-08-8
Price and Availability of CAS No. : 556803-08-8
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5mg $75 In-stock
10mg $120 In-stock
25mg $250 In-stock
50mg $400 In-stock
100mg $650 In-stock
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Cat. No. : HY-107712
M.Wt: 376.54
Formula: C18H24N4OS2
Purity: >98 %
Solubility: DMSO : 250 mg/mL (ultrasonic)
Introduction of 556803-08-8 :

TCN 213 is a selective, surmountable, glycine-dependentlly GluN1/GluN2A NMDAR antagonist with IC50s of 0.55, 3.5, 40 μM in the presence of 75, 750, 7500 nM glycine, respectively. TCN 213 can be used to monitor, pharmacologically, the switch in NMDAR expression in developing cortical neurones[1][2]. In Vitro: TCN 213 (30 µM) antagonizes NMDA-evoked currents in neurones transfected with GluN2A subunits[1].

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