3-Methyl-2-buten-1-ol
CAS No. : 556-82-1
(Synonyms: MBO321)
| Size | Price | Stock |
|---|---|---|
| 25g | $19 | In-stock |
| 100g | $48 | In-stock |
| 500g | $171 | In-stock |
| 1000g | $320 | In-stock |
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| Cat. No. : | HY-W013035 |
| M.Wt: | 86.13 |
| Formula: | C5H10O |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 100 mg/mL |
3-Methyl-2-buten-1-ol (MBO321) is an orally active endogenous metabolite found in pine trees and is used as a fragrance ingredient in cosmetics and detergents. 3-Methyl-2-buten-1-ol passes cell barrier. 3-Methyl-2-buten-1-ol reduces body weight in rats[1][2][3].
In Vitro:3-Methyl-2-buten-1-ol (100 μM, 120 min) pass the Caco-2 cell barrier quickly, with Papp of 37.3 μcm/s (recalculated donor concentration)[2].
In Vivo:3-Methyl-2-buten-1-ol (200-5000 ppm, drinking water, 90 days) decreases food and water consumption, body weight, food efficiency, and urinary volumer in rats[3].
3-Methyl-2-buten-1-ol (50-600 mg/kg, gavage, days 6-19 post coitum (pc)) shows unscheduled death of 1 dam on day 19 pc, transient salivation in all dams immediately between days 6-19 pc, transient occurrence of abdominal position, and lacrimation and/or piloerection shortly in rats[3].
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