Glycylglycine (Standard)


CAS No. : 556-50-3

(Synonyms: Gly-Gly (Standard); H-Gly-Gly-OH (Standard))

556-50-3
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Cat. No. : HY-D0889R
M.Wt: 132.12
Formula: C4H8N2O3
Purity: >98 %
Solubility: Acetone : 1 mg/mL (7.57 mM; Need ultrasonic); H2O : 130 mg/mL (983.95 mM; Need ultrasonic)
Introduction of 556-50-3 :

Glycylglycine (Standard) is the analytical standard of Glycylglycine (HY-D0889). This product is intended for research and analytical applications. Glycylglycine is a non-selective glycylglycine dipeptidase substrate and iNOS inhibitor. Glycylglycine can cross the cell membrane by passive diffusion and is hydrolyzed to glycine in the cell, participating in energy metabolism and antioxidant processes. Glycylglycine promotes spermatogonial stem cells (SSCs) proliferation, inhibits astrocyte overactivation and reduces nitric oxide (NO) release, while upregulating the expression of neurotrophic factors (such as PDGFA, FGF2, CNTF) to support nerve myelin repair. Glycylglycine can be used to study male reproductive biology (such as SSCs proliferation regulation) and neurodegenerative diseases (such as neuroprotective mechanisms in multiple sclerosis)[1][2].

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