5'-Guanylic acid (disodium salt)
CAS No. : 5550-12-9
(Synonyms: 5'-GMP (disodium salt); 5'-guanosine monophosphate (disodium salt))
| Size | Price | Stock |
|---|---|---|
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| 100g | $40 | In-stock |
| 500g | $143 | In-stock |
| 1000g | $250 | In-stock |
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| Cat. No. : | HY-W010970 |
| M.Wt: | 407.18 |
| Formula: | C10H12N5Na2O8P |
| Purity: | >98 % |
| Solubility: | H2O : 50 mg/mL (ultrasonic);DMSO : < 1 mg/mL (ultrasonic;warming;heat to 80°C) |
5'-Guanylic acid disodium salt is the disodium salt form of 5'-Guanylic acid (HY-N5134). 5'-Guanylic acid disodium salt is a purine nucleotide that participates in physiological processes such as energy metabolism, signal transduction, and gene expression regulation. 5'-Guanylic acid disodium salt regulates the expression of genes related to fatty acid metabolism. 5'-Guanylic acid disodium salt is the weak agonist for ionotropic glutamate receptors (iGluR), reduces the activity of the glutamatergic system and exhibits neuroprotective effect. 5'-Guanylic acid disodium salt also causes neuronal cell death at high concentrations[1][2][3].
In Vitro:5'-Guanylic acid disodium salt (50-500 μM, 48 h) regulates the expression of genes involved in fatty acid metabolism, affects fatty acid composition in Oncorhynchus mykiss hepatocytes, and regulates fatty acid metabolism[1].
In Vivo:5'-Guanylic acid disodium salt (10-150 mg/kg, ip, single dose) exhibits anti-anxiety effect in Wistar rats models[2].
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