Decylubiquinone
CAS No. : 55486-00-5
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| Cat. No. : | HY-121134 |
| M.Wt: | 322.44 |
| Formula: | C19H30O4 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Decylubiquinone is an analog of ubiquinone (coenzyme Q10). Decylubiquinone blocks reactive oxygen species (ROS) production in response to glutathione depletion and inhibits activation of the mitochondrial permeability transition[1].
In Vitro: Decylubiquinone (dUb; 10 μm for 6 hours) exerts its effects on ROS by either inhibition of ROS production by cytochrome bc1 or that it scavenged ROS produced[1].
Decylubiquinone inhibits both the dichlorofluorescein (DCF) fluorescence increase resulting from H2O2 treatment and the DCF fluorescence increase resulting after glutathione (GSH) depletion using diethylmaleate mitochondrially generated ROS)[1].
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