Trimethobenzamide (hydrochloride)
CAS No. : 554-92-7
(Synonyms: Ro 2-9578)
| Size | Price | Stock |
|---|---|---|
| 100mg | $96 | In-stock |
| 200mg | $132 | In-stock |
| 500mg | $204 | In-stock |
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| 5 g | Get quote | |
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| Cat. No. : | HY-12751A |
| M.Wt: | 424.92 |
| Formula: | C21H29ClN2O5 |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 100 mg/mL |
Trimethobenzamide hydrochloride is a blocker of the D2 receptor. Trimethobenzamide is an antiemetic used to prevent nausea and vomiting. IC50 & Target: D2 receptor[1] In Vitro: Trimethobenzamide is a (non-phenothiazine) benzamide antiemetic that acts centrally to block D2 receptors, thereby inhibiting the medullary chemoreceptor trigger zone by blocking emetic impulses to the vomiting center[1]. In Vivo: The oral bioavailability of Trimethobenzamide is 60% to 100%. The time to peak is about 45 minutes after oral administration and; Intramuscular (I.M.) administration about 30 minutes after intramuscular administration[1].
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