Vidarabine


CAS No. : 5536-17-4

(Synonyms: Ara-A; Adenine Arabinoside; 9-β-D-Arabinofuranosyladenine)

5536-17-4
Price and Availability of CAS No. : 5536-17-4
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500g $363 In-stock
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Cat. No. : HY-B0277
M.Wt: 267.25
Formula: C10H13N5O4
Purity: >98 %
Solubility: H2O : < 0.1 mg/mL;DMSO : 50 mg/mL (ultrasonic)
Introduction of 5536-17-4 :

Vidarabine (Ara-A) an antiviral agent which is active against herpes simplex and varicella zoster viruses[1][2]. Vidarabine has IC50s of 9.3 μg/ml for HSV-1 and 11.3 μg/ml for HSV-2[2]. Vidarabine also has anti-orthopoxvirus activity[3]. IC50 & Target:DNA/RNA Synthesis[1]
In Vitro: Vidarabine (Ara-A) is a nucleoside antibiotic isolated from Streptomyces antibioticus. It has some antineoplastic properties and has broad spectrum activity against DNA viruses in cell cultures and significant antiviral activity against infections caused by a variety of viruses such as the herpes viruses, the vaccinia VIRUS and varicella zoster virus[1].

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