Pentagastrin
CAS No. : 5534-95-2
(Synonyms: ICI-50123)
| Size | Price | Stock |
|---|---|---|
| 5mg | $60 | In-stock |
| 10mg | $96 | In-stock |
| 25mg | $180 | In-stock |
| 50mg | $300 | In-stock |
| 100mg | $432 | In-stock |
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| Cat. No. : | HY-A0261 |
| M.Wt: | 767.89 |
| Formula: | C37H49N7O9S |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic;warming;heat to 60°C);H2O : < 0.1 mg/mL (ultrasonic) |
Pentagastrin (ICI-50123) is a potent, selective Cholecystokinin B (CCKB) receptor agonist with an EC50 value of 11 nM. Pentagastrin enhances gastric mucosal defense mechanisms against acid and protects the gastric mucosa from experimental injury[1][2].
IC50 & Target:EC50: 11 nM (CCKB receptor)[1]
In Vitro:Pentagastrin (0.1-100 μM; GH3-cells) increases intracellular Ca2+ in a dose-dependent manner with a maximal increase of 2.77-fold[1].
Pentagastrin (0.1-100 μM; GH3-cells) bounds dose dependently to GH3 cells[1].
In Vivo:Pentagastrin (80 μg/kg/h; intravenous infusion) protects rat gastric mucosa from acidified Aspirin (HY-14654) injury[2].
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