Atractylodin


CAS No. : 55290-63-6

(Synonyms: Atractydin)

55290-63-6
Price and Availability of CAS No. : 55290-63-6
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Cat. No. : HY-N0238
M.Wt: 182.22
Formula: C13H10O
Purity: >98 %
Solubility: DMSO : ≥ 6 mg/mL
Introduction of 55290-63-6 :

Atractylodin (Atractydin) is an orally active active ingredient obtained from the rhizome of Atractylodes lancea and A. chinensis. Atractylodin is a natural insecticide. Atractylodin has anti-inflammatory activity[1][2][3]. In Vitro:Atractylodin (50 μM, 48 h) significantly inhibits tumor necrosis factor-α-induced activated B-nuclear factor-κ-light chain enhancer phosphorylation in HCT116 cells[2].
Atractylodin (10, 20, 40 μM, 24 h) alleviates HFD-induced NAFLD by inhibiting hepatocyte sideroptosis[3].
In Vivo:Atractylodin (40 mg/kg intraperitoneally injected for 14 days) can improve the survival rate of mice in a mouse model of colitis induced by sodium dextran sulfate[2].
Atractylodin (20, 40, 80 mg/kg, gavage) alleviates the oxidative stress of HepG2 cells induced by high-fat diet (HFD) and palmitic acid (PA) in mice[3].

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