DB07107
CAS No. : 552332-71-5
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| Cat. No. : | HY-123390 |
| M.Wt: | 370.45 |
| Formula: | C23H22N4O |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
DB07107 is a potent drug resistant T315I mutant Bcr-Abl tyrosine kinase inhibitor. DB07107 is also a potent Akt1 inhibitor with an IC50 value of 360 nM[1][2]. In Vitro: DB07107 is more effective in blocking drug-resistant T315I mutant than the wild-type Bcr-Abl. DB07107 (C23H22N4O) from DrugBank showed the highest binding energy with XP score of -14.045 kcal/mol[1].
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