T16Ainh-A01
CAS No. : 552309-42-9
| Size | Price | Stock |
|---|---|---|
| 5mg | $45 | In-stock |
| 10mg | $78 | In-stock |
| 25mg | $170 | In-stock |
| 50mg | $288 | In-stock |
| 100mg | $460 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
or Fax: (86)21-58955996
Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-100612 |
| M.Wt: | 416.52 |
| Formula: | C19H20N4O3S2 |
| Purity: | >98 % |
| Solubility: | DMF : ≥ 10 mg/mL;DMSO : 83.33 mg/mL (ultrasonic) |
T16Ainh-A01, an aminophenylthiazole, is a potent transmembrane protein 16A (TMEM16A) inhibitor, inhibiting TMEM16A-mediated chloride currents with an IC50 value of ~1 µM. TMEM16A (ANO1) functions as a calcium-activated chloride channel (CaCC)[1][2].
IC50 & Target: TMEM16A[1].
In Vitro: T16Ainh-A01 (0.3-30 μM) significantly reduces both inward and outward components of IClCa, and inhibits IClCa in RUICC without significantly affecting L-type Ca2+ current[1].
T16Ainh-A01 (10 μM) inhibits nearly completely TMEM16A chloride current (induced by 275 nM free calcium in the pipette) at all voltages, indicating a voltage-independent block mechanism[2].
Lorem ipsum dolor sit amet, consectetur adipisicing elit. Autem earum hic iste maiores, nam neque rem suscipit. Adipisci consequatur error exercitationem fugit ipsam optio qui, quibusdam repellendus sed vero! Debitis.
Inquiry Information- Product Name:
- T16Ainh-A01
- Cat. No.:
- HY-100612
- Quantity:
Your information is safe with us.