Dimetridazole
CAS No. : 551-92-8
(Synonyms: 1,2-Dimethyl-5-nitroimidazole)
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| Cat. No. : | HY-B1244 |
| M.Wt: | 141.13 |
| Formula: | C5H7N3O2 |
| Purity: | >98 % |
| Solubility: | DMSO : 50 mg/mL (ultrasonic) |
Dimetridazole is a nitroimidazole antibiotic. Dimetridazole inhibits protein synthesis in cultures of Campylobacter jejuni. Dimetridazole is genotoxic. Dimetridazole can be used in the research of protozoal and bacterial infections[1][2][3][4].
In Vitro:Dimetridazole (50 μg/mL; 2-3 h) blocks protein synthesis in Campylobacter jejuni cultures[2].
Dimetridazole shows activity against 16 clinical isolates of Bacteroides fragilis with a geometric mean MIC of 6.39 μM[3].
Dimetridazole (70-354.3 μM; 1 h) induces dose-dependent DNA damage in human lymphocytes under aerobic conditions[4].
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