ERB-196
CAS No. : 550997-55-2
(Synonyms: WAY-202196)
| Size | Price | Stock |
|---|---|---|
| 5mg | $460 | In-stock |
| 10mg | $740 | In-stock |
| 25mg | $1560 | In-stock |
| 50mg | $2500 | In-stock |
| 100mg | $4000 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-19468 |
| M.Wt: | 279.27 |
| Formula: | C17H10FNO2 |
| Purity: | >98 % |
| Solubility: | Ethanol : 16 mg/mL (ultrasonic) |
ERB-196 is a nonsteroidal selective estrogen receptor-β (ERβ) agonist. IC50 & Target: ERβ[1] In Vivo: ERB-196 is a nonsteroidal selective estrogen receptor-β (ERβ) agonist. ERB-196 significantly reduces histopathologic evidence of injury to the gastrointestinal mucosal surface (0.7±0.1 vs. 2.3±0.2 for control; p<0.05). The mucosal mass of 10-cm segments of small bowel mucosa shows better preservation of mucosal mass than control treatment (63±20 [ERB-196] vs. 31±24 [control]), but this difference fails to reach statistical significance (p<0.06). The administration of ERB-196 is highly effective in the prevention of lethality. Consistent with the neutropenic rat model, ERB-196 significantly increases survival when compare with vehicle control[1].
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