NAADP


CAS No. : 5502-96-5

5502-96-5
Price and Availability of CAS No. : 5502-96-5
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1mg $250 In-stock
5mg $640 In-stock
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Cat. No. : HY-103317
M.Wt: 744.39
Formula: C21H27N6O18P3
Purity: >98 %
Solubility: H2O : 50 mg/mL (ultrasonic;warming)
Introduction of 5502-96-5 :

NAADP, a nucleotide, is a Ca2+-mobilizing second messenger. NAADP is essential for initiation of Ca2+ signaling[1][2]. In Vitro: NAADP (2.5-10 μM) induces Ca2+ release from acidic intracellular stores in cytotoxic T lymphocytes[2].
NAADP (10 μM, 30 min) stimulates cytolytic granule exocytosis in cytotoxic T lymphocyte[2].
In Vivo: NAADP (0.181 mg/kg, i.v.) promotes autophagosome formation and protects the hepatocytes from injury in mice induced by LPS/GalN[3].

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