Embelin
CAS No. : 550-24-3
(Synonyms: Embelic acid; Emberine; NSC 91874)
| Size | Price | Stock |
|---|---|---|
| 5mg | $42 | In-stock |
| 10mg | $66 | In-stock |
| 25mg | $120 | In-stock |
| 50mg | $190 | In-stock |
| 100mg | $310 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-17473 |
| M.Wt: | 294.39 |
| Formula: | C17H26O4 |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 50 mg/mL |
Embelin (Embelic acid), a potent, nonpeptidic XIAP inhibitor (IC50=4.1 μM), inhibits cell growth, induces apoptosis, and activates caspase-9 in prostate cancer cells with high levels of XIAP. Embelin blocks NF-kappaB signaling pathway leading to suppression of NF-kappaB-regulated antiapoptotic and metastatic gene products. Embelin also induces autophagic and apoptotic cell death in human oral squamous cell carcinoma cells[1][2][3]. In Vitro: Embelin (Embelic acid) has a minimal effect on normal prostate epithelial and fibroblast cells with low levels of XIAP[1].
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