Atropine (sulfate)
CAS No. : 55-48-1
(Synonyms: Tropine tropate (sulfate); DL-Hyoscyamine (sulfate); Sulfatropinol)
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| Cat. No. : | HY-B1205A |
| M.Wt: | 338.41 |
| Formula: | C17H23NO3.1/2H2SO4 |
| Purity: | >98 % |
| Solubility: | H2O : 100 mg/mL (ultrasonic);DMSO : 62.5 mg/mL (ultrasonic) |
Atropine (Tropine tropate) sulfate is a competitive muscarinic acetylcholine receptor (mAChR) antagonist with IC50 values of 0.39 and 0.71 nM for Human mAChR M4 and Chicken mAChR M4, respectively. Atropine sulfate inhibits ACh-induced relaxations in human pulmonary veins. Atropine sulfate can be used for research of anti-myopia and bradycardia[1][2][3][4]. IC50 & Target:IC50: 0.39 nM (Human mAChR M4) and 0.71 nM (Chicken mAChR M4)[3] In Vitro: Atropine (Tropine tropate; 1 μM; pulmonary veins and arteries) sulfate inhibits ACh-induced relaxations in human pulmonary veins[4]. In Vivo: Atropine (Tropine tropate; 10 mg/kg; i.p.; once, for 40 minutes; Peromyscus sp.) sulfate inhibits the cardiac arrhythmia which normally occurs throughout torpor[2].
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