Benzamide
CAS No. : 55-21-0
(Synonyms: Benzenecarboxamide; Phenylamide)
| Size | Price | Stock |
|---|---|---|
| 25g | $11 | In-stock |
| 100g | $25 | In-stock |
| 500g | $77 | In-stock |
| 1000g | $131 | In-stock |
| > 2 kg | Get quote | |
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| Cat. No. : | HY-Z0283 |
| M.Wt: | 121.14 |
| Formula: | C7H7NO |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
Benzamide (Benzenecarboxamide) is a potent poly(ADP-ribose) polymerase (PARP) inhibitor. Benzamide has protective activity against both glutamate- and methamphetamine (METH)-induced neurotoxicity in vitro. Benzamide can attenuate the METH-induced dopamine depletions and exhibits neuroprotective activity in mice, also has no acute effect on striatal dopamine metabolism and does not reduce body temperature[1].
In Vivo: Benzamide (160 mg/kg; IP, 2 injection by a 4 h interval) attenuates the METH-induced dopamine depletions[1].
Benzamide (160 mg/kg; IP, single dosage) has no acute effect on striatal dopamine metabolism and does not reduce body temperature[1].
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