CAS No. : 55-06-1
(Synonyms: Triiodothyronine (sodium); 3,3',5-Triiodo-L-thyronine (sodium); T3 (sodium))
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| 500mg | $144 | In-stock |
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| Cat. No. : | HY-A0070 |
| M.Wt: | 672.96 |
| Formula: | C15H11I3NNaO4 |
| Purity: | >98 % |
| Solubility: | DMSO : 5.56 mg/mL (ultrasonic;warming;heat to 60°C);H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 60°C) |
Liothyronine sodium is an active form of thyroid hormone. Liothyronine sodium is a potent thyroid hormone receptors TRα and TRβ agonist with Kis of 2.33 nM for hTRα and hTRβ, respectively[1][2][3]. IC50 & Target:TRβ1[1][2] In Vitro: Liothyronine (T3, 100 nM) sodium stimulates the proliferation of hepatocarcinema cells in which TRβ1 is overexpressed[1]. Liothyronine sodium binds to human β1 thyroid hormone receptor (hTRβ1), and changes its conformation. Liothyronine sodium promotes growth, induces differentiation and regualtes metabolic effects[2].
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