Liothyronine (sodium)


CAS No. : 55-06-1

(Synonyms: Triiodothyronine (sodium); 3,3',5-Triiodo-L-thyronine (sodium); T3 (sodium))

55-06-1
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Cat. No. : HY-A0070
M.Wt: 672.96
Formula: C15H11I3NNaO4
Purity: >98 %
Solubility: DMSO : 5.56 mg/mL (ultrasonic;warming;heat to 60°C);H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 60°C)
Introduction of 55-06-1 :

Liothyronine sodium is an active form of thyroid hormone. Liothyronine sodium is a potent thyroid hormone receptors TRα and TRβ agonist with Kis of 2.33 nM for hTRα and hTRβ, respectively[1][2][3]. IC50 & Target:TRβ1[1][2] In Vitro: Liothyronine (T3, 100 nM) sodium stimulates the proliferation of hepatocarcinema cells in which TRβ1 is overexpressed[1]. Liothyronine sodium binds to human β1 thyroid hormone receptor (hTRβ1), and changes its conformation. Liothyronine sodium promotes growth, induces differentiation and regualtes metabolic effects[2].

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