(Rac)-Shikonin


CAS No. : 54952-43-1

(Synonyms: Shikalkin)

54952-43-1
Price and Availability of CAS No. : 54952-43-1
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10mg $40 In-stock
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Cat. No. : HY-N6004
M.Wt: 288.30
Formula: C16H16O5
Purity: >98 %
Solubility: DMSO : 125 mg/mL (ultrasonic)
Introduction of 54952-43-1 :

(Rac)-Shikonin (Shikonin) possesses anti-tumor activity. (Rac)-Shikonin (Shikonin) circumvents cancer agent resistance by induction of a necroptotic death[1][2]. In Vitro: Shikonin shows a similar potency toward drug-sensitive cancer cell lines (MCF-7 and HEK293) and their drug-resistant lines overexpressing P-glycoprotein, Bcl-2, or Bcl-xL, which account for most of the clinical cancer drug resistance[2].

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