Droperidol
CAS No. : 548-73-2
(Synonyms: Dehydrobenzperidol)
| Size | Price | Stock |
|---|---|---|
| 100mg | $50 | In-stock |
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| Cat. No. : | HY-B1240 |
| M.Wt: | 379.43 |
| Formula: | C22H22FN3O2 |
| Purity: | >98 % |
| Solubility: | H2O : ≥ mg/mL;DMSO : 33.33 mg/mL (ultrasonic) |
Droperidol (Dehydrobenzperidol) is a butyrophenone pamine-2 receptor antagonist that inhibits the activation of GABA(A) and neuronal nicotinic receptors (nAChR), with IC50 values of 12.6 nM and 5.8 μM. Droperidol has anesthetic and sedative properties[1][2]. In Vitro: Doperidol (100 μM) activates the GABAA receptor in the absence of GABA[1]. In Vivo: Doperidol (0.125-4 mg/kg, intravenous injection, single dose) can slow down a dog's breathing, heart rate, and reduce blood pressure, cardiac output, and myocardial contractility[2].
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