GATA4-NKX2-5-IN-1
CAS No. : 544681-96-1
| Size | Price | Stock |
|---|---|---|
| 5mg | $280 | In-stock |
| 10mg | $380 | In-stock |
| 25mg | $600 | In-stock |
| 50mg | $810 | In-stock |
| 100mg | $1100 | In-stock |
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| Cat. No. : | HY-103484 |
| M.Wt: | 349.43 |
| Formula: | C21H23N3O2 |
| Purity: | >98 % |
| Solubility: | DMSO : 83.33 mg/mL (ultrasonic;warming;heat to 60°C) |
GATA4-NKX2-5-IN-1 (Compound 3) dose-dependently inhibits the GATA4–NKX2-5 transcriptional synergy with an IC50 of 3 μM. GATA4-NKX2-5-IN-1 exhibits no activity on the protein kinases involved in the regulation of GATA4 phosphorylation, and it modulates the hypertrophic agonist-induced cardiac gene expression[1]. IC50 & Target: IC50: 3 μM (GATA4–NKX2-5)[1]
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