MRS1845
CAS No. : 544478-19-5
| Size | Price | Stock |
|---|---|---|
| 5mg | $150 | In-stock |
| 10mg | $240 | In-stock |
| 25mg | $480 | In-stock |
| 50mg | $750 | In-stock |
| 100mg | $1100 | In-stock |
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| 500 mg | Get quote | |
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| Cat. No. : | HY-103310 |
| M.Wt: | 398.41 |
| Formula: | C21H22N2O6 |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 125 mg/mL;DMSO : 125 mg/mL (ultrasonic);DMSO : ≥ 83.33 mg/mL |
MRS1845 is a selective store-operated calcium (SOC) channel inhibitor with an IC50 of 1.7 μM[1]. MRS1845 is an ORAI1 inhibitor[2][3]. MRS1845 is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
IC50 & Target: Ca2+ channel[1]
In Vitro: Treatment with MRS1845 (10 μM) virtually disrupts the effects of β-glycerophosphate on store-operated Ca2+ entry (SOCE)[2].
MRS1845 (10 μM) significantly decreases SOCE and virtually abolishes the increase of SOCE following placental growth factor (PlGF) treatment[3].
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