(Rac)-Norcantharidin
CAS No. : 5442-12-6
(Synonyms: (Rac)-NCTD)
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| Cat. No. : | HY-N0585 |
| M.Wt: | 168.15 |
| Formula: | C8H8O4 |
| Purity: | >98 % |
| Solubility: | DMSO : 125 mg/mL (ultrasonic);DMSO : 125 mg/mL (ultrasonic) |
(Rac)-Norcantharidin ((Rac)-NCTD) is the racemic form of Norcantharidin. Norcantharidin is a demethylated derivative of Cantharidin (HY-N0209) and has antitumor activity[1][2][3]. In Vitro:(Rac)-Norcantharidin (0-20 μg/mL; 0-48 h) can inhibit cell proliferation, induce cell cycle arrest and apoptosis, suppress migration and angiogenic activity, and downregulate the expression of related genes such as METTL16 and MAT2A in human ovarian cancer cell lines ES2 and SKOV3[3]. In Vivo:(Rac)-Norcantharidin (5-10 mg/kg; intraperitoneal injection; three times a week; 3 weeks) exhibits antitumor activity in a human ovarian cancer xenograft nude mouse model[3].
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