Ethyl linoleate
CAS No. : 544-35-4
(Synonyms: Linoleic Acid ethyl ester; Mandenol)
| Size | Price | Stock |
|---|---|---|
| 100mg | $30 | In-stock |
| 500mg | $40 | In-stock |
| 1g | $45 | In-stock |
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| Cat. No. : | HY-W013812 |
| M.Wt: | 308.50 |
| Formula: | C20H36O2 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
Ethyl linoleate (Linoleic Acid ethyl ester) is an orally active unsaturated fatty acid. Ethyl linoleate inhibits the Akt/GSK3β/β-catenin signaling pathway and the activation of NF-κB. Ethyl linoleate induces heme oxygenase-1 and inhibits tyrosinase. Ethyl linoleate has whitening and anti-inflammatory effects. Ethyl linoleate promotes compound absorption. Ethyl linoleate has a significant influence on atherosclerosis. Ethyl linoleate is used in the research of inflammatory diseases. Ethyl linoleate can be used in cosmetics[1][2][3][4][5][6]
In Vitro: Ethyl linoleate (400 μM; 48 h) significantly inhibits melanin content and intracellular tyrosinase activity in α-MSH (HY-P0252)-induced B16F10 cells[1].
Ethyl linoleate (1-20 μM; 1-24 h) attenuates Lipopolysaccharide-induced pro-inflammatory cytokine production by inducing heme oxygenase-1 in RAW264.7 cells[2].
In Vivo: Ethyl linoleate (10% added to the high-cholesterol diet; p.o.; 12 weeks) has a significant effect on atherosclerosis induced by a high cholesterol diet in rabbits[5].
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