BMS-433771
CAS No. : 543700-68-1
| Size | Price | Stock |
|---|---|---|
| 5mg | $620 | In-stock |
| 10mg | $770 | In-stock |
| 25mg | $1100 | In-stock |
| 50mg | $1750 | In-stock |
| 100mg | $2800 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-120632 |
| M.Wt: | 377.44 |
| Formula: | C21H23N5O2 |
| Purity: | >98 % |
| Solubility: | H2O : 2.5 mg/mL (ultrasonic;adjust pH to 4 with HCl);DMSO : 6.25 mg/mL (ultrasonic;warming;heat to 60°C) |
BMS-433771 is a potent orally active inhibitor of respiratory syncytial virus (RSV). BMS-433771 is active against both A and B groups of RSV, with an average EC50 of 20 nM. BMS-433771 can be used for the research of respiratory tract disease[1][2].
IC50 & Target:EC50: 20 nM (RSV)[1]
In Vitro:BMS-433771 has inhibitory against both A and B groups of RSV, with an average EC50 of 20 nM[1].
BMS-433771 can inhibit viral F protein-induced membrane fusion[1].
In Vivo:BMS-433771 (p.o.; 1-200 mg/kg; single or bid 4 days) shows prophylactic efficacy via oral dosing, but has considerable pharmacodynamic differences between the two rodent models[2]
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