Heptaminol (hydrochloride)
CAS No. : 543-15-7
(Synonyms: RP-2831 hydrochloride)
| Size | Price | Stock |
|---|---|---|
| 25mg | $35 | In-stock |
| 50mg | $50 | In-stock |
| 100mg | $70 | In-stock |
| 200mg | $106 | In-stock |
| 500mg | $178 | In-stock |
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| Cat. No. : | HY-B1231 |
| M.Wt: | 181.70 |
| Formula: | C8H20ClNO |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 100 mg/mL;H2O : ≥ 100 mg/mL |
Heptaminol (RP-2831) hydrochloride is a vasoconstrictor used in the study of hypotension, especially orthostatic hypotension. Heptaminol is also a skin cancer proliferation inhibitor that inhibits immune inflammation induced by the tumor promoting factor 12-O-tetradecanoylphorbol-13-acetate (TPA) in an NO-dependent manner. Heptaminol also acts as a sympathomimetic amine, exerting indirect sympathetic effects. Heptaminol is also an antagonist of catecholamine release and uptake and can increase intracellular free calcium levels[1][2][3].
In Vivo:Heptaminol hydrochloride (12 μL; 50% water/acetone) stimulates NO synthesis from constitutive NOS and attenuates TPA-induced depletion of NK cells at the edge of the mouse ear. Heptaminol hydrochloride exerts anti-proliferative and anti-inflammatory effects on TPA, suggesting important anti-tumor function[2].
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