R(+)-Methylindazone


CAS No. : 54197-31-8

(Synonyms: R(+)-IAA-94)

54197-31-8
Price and Availability of CAS No. : 54197-31-8
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Cat. No. : HY-12693
M.Wt: 357.23
Formula: C17H18Cl2O4
Purity: >98 %
Solubility: DMSO : ≥ 100 mg/mL;H2O : 0.1 mg/mL (ultrasonic)
Introduction of 54197-31-8 :

R(+)-Methylindazone (R(+)-IAA-94) is a potent indanyloxyacetic acid blocker of epithelial chloride channels. R(+)-Methylindazone inhibits Nef-sdAb19 (single-domain antibody) interaction and binds to negative factor (Nef)[1][2][3]. In Vitro: IAA-94 has been employed in modulating chloride channel function to probe the dynamics and function of the channels. The high affinity of IAA-94 for the chloride channel has been exploited for isolation and reconstitution of these proteins[1][2].

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