Flecainide
CAS No. : 54143-55-4
| Size | Price | Stock |
|---|---|---|
| 5mg | $38 | In-stock |
| 10mg | $60 | In-stock |
| 25mg | $100 | In-stock |
| 50mg | $160 | In-stock |
| 100mg | $248 | In-stock |
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| Cat. No. : | HY-W010950 |
| M.Wt: | 414.34 |
| Formula: | C17H20F6N2O3 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
Flecainide is an orally active antiarrhythmic agent. Flecainide can block sodium channels and inhibit calcium ion release mediated by the cardiac ryanodine receptor (RyR2). Flecainide can be used in the research of diseases such as catecholaminergic polymorphic ventricular tachycardia (CPVT)[1][2]. In Vitro:Flecainide (500 nM) significantly reduces irregular Ca2+ release in single cardiomyocytes derived from ATS-iPSCs[1]. In Vivo:Flecainide (20 mg/kg; intraperitoneal injection; single dose) completely inhibits catecholamine-induced ventricular arrhythmias in Casq2 knockout mice[2].
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